A symposium has been organized to honour the retirements of the University of British Columbia "Big 4": John Phillips, Peter Hochachka, Dave Randall and Dave Jones, and the collective contribution these four have made to comparative biochemistry and physiology. It will be held as a one day satellite symposium of the Conference on "The Power of Comparative Physiology: Evolution, Integration and Applied" sponsored by the American Physiological Society in San Diego this August. Full details are now available on the web at
www.science.ubc.ca/~biomania/thebig4.htm.