SICB Annual Meeting 2019
January 3-7, 2019
Tampa, FL

January 5 - Symposium S6: Beyond the powerhouse: integrating mitonuclear evolution, physiology, and theory in comparative biology

Mitonuclear Reckoning by Megan Parker
Life depends on the efficient production of useable energy. Complex life, in the form of eukaryotes, exists only with a continuous and rich supply of energy from oxidative phosphorylation in mitochondria. In turn, mitochondrial function is dictated by the coordinated efforts of proteins and other products encoded by both the nuclear and mitochondrial genomes. It follows that selection for efficient mitonuclear co-function is critical and mitonuclear compatibility is a "rule" for complex life. Supporting the tenet of mitonuclear compatibility, it has been proposed that the necessity for mitonuclear coadaptation to enable cellular respiratory function could underlie core evolutionary innovations and concepts including: the evolution of organismal complexity, the origin of sex and two sexes in eukaryotes, environmental adaptation, sexual selection, and speciation. Despite the ubiquity of co-functioning mitochondrial and nuclear genes in eukaryotes, our understanding of the contribution of mitonuclear genetics to eukaryotic fitness and higher-level phenotypes remains very incomplete. In this symposium experts in mitonuclear genomics and physiology come together with the goals of informing the community about the importance of mitonuclear interactions for ecology and evolution, developing new tools to assess mitochondrial function and quantify mitonuclear selection, and discuss how measures of mitonuclear function and compatibility translate into complex eukaryotic phenotypes.

Sponsors: DCPB, DIZ, DPCB, The Crustacean Society


  • Justin Havird
  • Geoffrey Hill


S6-1 Saturday, Jan. 5, 08:00 DOWLING, DK: Maternal inheritance of mitochondria, and implications for male health

S6-2 Saturday, Jan. 5, 08:30 JIMENEZ, A.G.*; ANDERSON, K; O'CONNOR, E; TOBIN, K; WINWARD, J; WINNER, R; CHINCHILLI, E; DOWNS, C. J.; CARLSON, K; DOWNS, C. J.: Does Oxidative Stress Differ Between Mammals and Birds?

S6-3 Saturday, Jan. 5, 09:00 GREENWAY, R.*; HAVIRD, J.C.; KELLEY, J.L.; TOBLER, M.: The role of mitonuclear incompatibilities during ecological speciation in extremophile poeciliid fishes

S6-4 Saturday, Jan. 5, 09:30 SOKOLOVA, Inna: Mitochondrial adaptations to fluctuating oxygen levels in hypoxia-tolerant marine bivalves

S6-5 Saturday, Jan. 5, 10:30 HAVIRD, JC: Mitonuclear Ecophysiology: The Cooperative Genomics of Environmental Adaptation

S6-6 Saturday, Jan. 5, 11:00 WATSON, Eric T.*; EDMANDS, Suzanne: Mitonuclear coevolution and the genetics of speciation in Tigriopus californicus.

S6-7 Saturday, Jan. 5, 11:30 HILL, G. E.; HILL, Geoffrey: Speciation and Sexual Selection as Processes to Maintain Mitonuclear Coadapation

S6-8 Saturday, Jan. 5, 13:30 MONTOOTH, KL*; DHAWANJEWAR, A; MEIKLEJOHN, CD: Temperature-sensitive reproduction and the physiological and evolutionary potential for Mother's Curse

S6-9 Saturday, Jan. 5, 14:00 HOOD, Wendy*; WILLIAMS, Ashley; HILL, Geoffrey : Mitochondrial Replication Error and Senescence

S6-10 Saturday, Jan. 5, 14:30 WERNICK, RI; CHRISTY, SF; HOWE, DK; SULLINS, JA; RAMIREZ, JF; SARE, M; PENLEY, MJ; ESTES, S*; DENVER, DR; ESTES, S*: Sex and mitonuclear adaptation in experimental C. elegans populations

S6-11 Saturday, Jan. 5, 15:00 HEALY, TM; MCKENZIE, JL; CHUNG, DJ; BRENNAN, RS; WHITEHEAD, A; SCHULTE, PM*; SCHULTE, Patricia: Mitochondrial physiology, mitonuclear interactions, and adaptation to environmental stressors